Gout is a common type of inflammatory arthritis that causes sudden and severe swelling, pain, and stiffness in a joint. It typically occurs in the joint in the big toe. However, it also often affects the knee.
Pain on the outer (or lateral) part of the knee can be caused by an injury. It may also be the result of inflammation in a band of tough fibrous tissue that runs down the outside of the thigh, and attaches to the front of the tibia (shin bone). Pain in this area may also be caused by arthritis.
Among patients with normal renal function at baseline who are treated with a high-dose antibiotic-loaded bone cement (ALBC) spacer and systemic antibiotic therapy after resection of a periprosthetic joint infection (PJI) following a primary total knee arthroplasty (TKA), 14 percent develop acute kidney injury (AKI), according to a study published online March 29 in The Journal of Bone & Joint Surgery.
The research is intended to address a knowledge gap on the use of tranexamic acid, a drug that is currently used in the majority of patients undergoing hip and knee replacement surgery. The current study adds weight to the conclusion of smaller prior studies that show there is no evidence suggesting the drug carries more complications in high-risk patients.